MALIGNANT NEOPLASM OF THE URINARY SYSTEM WITH MULTIPLE BONE METASTASES

Abstract

In metastatic renal cell carcinoma (mRCC), bone is the second most common site of metastases, occurring in one third of patients. Most bone metastases are found in the sacrum, pelvis, spine and proximal limbs. In addition, the majority of bone metastases are osteolytic with elements of destruction; mixed metastases also occur. This predisposes patients to skeletal events such as pathological fracture, spinal cord compression, which implies the prescription of radiation therapy or bone surgery.